Prevalent cases ulcerative colitis are expected to increase, although the magnitude differs between countries.
By Nicola Leckenby, Epidemiologist
23 June 2016
I joined Datamonitor Healthcare as an Epidemiologist in 2015. Prior to this, I obtained an MSc (with Distinction) in Pub...
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Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by inappropriate diffuse inflammation of the rectal and colonic mucosa, which occurs in the innermost layer of intestinal lining. It is a chronic, incurable disease with low mortality that is generally diagnosed in adolescence and early adulthood. UC is currently an idiopathic condition, the pathogenesis of which is yet to be fully elucidated. However, it is known to involve an interaction between genetics, the immune system, and environmental factors.
Datamonitor Healthcare estimates that in 2015, there were 2.1 million diagnosed prevalent cases of UC across the US, Japan, and five major EU markets (France, Germany, Italy, Spain, and the UK). The prevalence of UC is expected to increase to 2.5 million in 2035 (16.6% increase). All analyzed countries are expected to experience an increase, with the largest increase expected in Spain. The forecasted increase in prevalent cases is due to evidence showing a consistent increase in prevalence proportions in analyzed countries. One driver of the increasing prevalence of UC is the phenomenon of compounding prevalence; a large rise in prevalence due to cumulative addition of incident cases in a chronic disease such as UC that has a young age of onset and low mortality.
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